Killer Instinct plays like many other fighting games, in which the player controls a character to beat an opponent in a one-on-one encounter. Ultratech also discovers a technology to make bridges between dimensions, and releases a two-headed, one-eyed, satyr monster called Eyedol from this dimensional prison. Along with regular participants, experimental creatures created by Ultratech also fight in the tournament so their strength can be tested. Ultratech is a very powerful megacorporation which organises a tournament called Killer Instinct. Retrospective lists by various publications included it among the best fighting games of all time. A port of the original game is included with the 2013 game under the title Killer Instinct Classic. Critically acclaimed, Killer Instinct was followed by a sequel, the 1996 arcade game Killer Instinct 2, later ported to the Nintendo 64 as Killer Instinct Gold, as well as a 2013 revival of the franchise as a launch title for Xbox One.

Also featured in the game are 'combo breakers', special defensive moves that can interrupt combos. The game also introduced 'auto-doubles', a feature which allows players to press a certain sequence of buttons to make characters automatically perform combos on opponents. The player that depletes the other player's life bars first wins the match. Instead of fighting enemies in best-of-three rounds bouts, each player has two life bars. Killer Instinct features several gameplay elements unique to fighting games of the time. The story was adapted in a limited comic book series published under the short-lived Acclaim Comics imprint. The game's plot involves an all-powerful corporation organising a fighting tournament. It was released as an arcade game in the fall of 1994 and, the following year, ported to the Super Nintendo Entertainment System (SNES) and the Game Boy. Killer Instinct is a fighting game developed by Rare and published by Midway and Nintendo. Mark Betteridge, Chris Tilston, Martin Hollis. This game can be played also in a version for Game Boy. The following emulators are available for this game: NeptunJS (JavaScript), Nesbox (Flash) and Retro (JavaScript).

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